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Hepatitis C is a serious liver disease caused by the hepatitis C virus. A virus is a type of "germ" that is much smaller than a cell. Viruses copy themselves in cells, and this causes the disease.
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Severe Fibrosis Calculator
The Virahep-C Model predicts severe liver fibrosis and was developed based on a sample of treatment naïve African American and Caucasian American participants in the Virahep-C study who had chronic hepatitis C virus infection with genotype 1. The model uses including age, race, AST, platelet count, and alkaline phosphatase.
The accuracy of the Virahep-C model to predict the presence or absence of severe liver fibrosis was assessed using various cut-off values
More information can be found in the manuscript: Fontana RJ et al. Modeling hepatic fibrosis in African American and Caucasian American patients with chronic hepatitis C virus infection. Hepatology 2006;44:925-935.
DISCLAIMER: This calculator of the predicted probability of severe fibrosis is not intended to be used in place of clinical judgment or other assessments in the determination of liver fibrosis.
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