The Epidemiology Data Center (EDC) was established in 1980 as a section of the Department of Epidemiology in the Graduate School of Public Health at the University of Pittsburgh. It was founded by Katherine M. Detre, M.D., Dr.P.H., and is under the co-direction of Sheryl F. Kelsey, Ph.D., Steven H. Belle, Ph.D. and Stephen R. Wisniewski, Ph.D.

The EDC has collaborated in over 100 research studies sponsored by the National Institutes of Health and other agencies. Presently, the EDC coordinates data management and analysis activities for 26 research projects sponsored by federal agencies as well as by industry.

The current studies represent a variety of scientific designs including clinical trials, registries, and case control studies. The successful coordination of our research requires that we facilitate national and global communication among a number of institutions worldwide.

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American Journal of Epidemiology, April 2010
Obesity in the United States has reached epidemic proportions and carries an excess risk of stroke, cardiovascular disease, and mortality. The vascular effects of obesity have been documented among adolescents and young adults, and it has been suggested that the decline in cardiovascular disease rates over the last decade is coming to an end because of the vascular effects of the obesity epidemic.

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The MINT Trial is a randomized clinical trial that will compare a liberal versus restrictive transfusion strategy in patients with coronary artery disease. Specifically the trial will evaluate the differences in hemoglobin concentrations, number of units of red blood cells transfused, cardiac events, and mortality in subjects randomized to the liberal versus the restrictive transfusion arm.
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The Hepatitis B Research Network brings together clinical centers with expertise in caring for patients with chronic hepatitis B virus (HBV) infection. An estimated 2 billion people worldwide have been infected with HBV and about 400 million persons are living with chronic HBV infection.
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The Cool Kids Trial is clinical trial of moderate hypothermia (32-33º C) as a treatment following severe traumatic brain injury in children as part of the Pediatric Traumatic Brain Injury Consortium (PTBIC).