The Epidemiology Data Center (EDC) was established in 1980 as a section of the Department of Epidemiology in the Graduate School of Public Health at the University of Pittsburgh. It was founded by Katherine M. Detre, M.D., Dr.P.H., and is under the co-direction of Sheryl F. Kelsey, Ph.D., Steven H. Belle, Ph.D. and Stephen R. Wisniewski, Ph.D.
The EDC has collaborated in over 100 research studies sponsored by the National Institutes of Health and other agencies. Presently, the EDC coordinates data management and analysis activities for 26 research projects sponsored by federal agencies as well as by industry.
The current studies represent a variety of scientific designs including clinical trials, registries, and case control studies. The successful coordination of our research requires that we facilitate national and global communication among a number of institutions worldwide.
Troponin and Cardiac Events In Stable Ischemic Heart Disease and Diabetes
New England Journal of Medicine, August 2015
Cardiac troponin concentrations are used to identify patients who would benefit from urgent revascularization for acute coronary syndromes. We hypothesized that troponin could be used to identify type 2 diabetes patients with stable ischemic heart disease who would benefit from prompt coronary revascularization.
Comprehensive Cardiovascular Risk Factor Control Improves Survival: The Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) Trial
Journal of the American College of Cardiology, August 2015
This study aimed to quantify the association between the achievement of multiple risk factor goals through protocol-guided intensive medical therapy in the Bypass Angioplasty Investigation Revascularization 2 Diabetes (BARI 2D) trial and cardiovascular events and mortality.
A study led by Samar El Khoudary, who holds a Ph.D. in epidemiology at the University of Pittsburgh Graduate School of Public Health, details an association between lower levels of the sex hormone estradiol and higher concentrations of small cholesterol-carrying lipoproteins that are known to cause the buildup of plaque in the arteries.
Approaches and Decisions in Acute Pediatric TBI Trial (ADAPT) is an international research study designed to evaluate the impact of interventions on the outcomes of children with severe traumatic brain injury. It is seen as an important step towards understanding the various approaches to managing the care of children with traumatic brain injuries.
New research from the University of Pittsburgh suggests that doubts raised recently about the protective effects of high density lipoprotein (HDL), or “good,” cholesterol by a genetic study and several recent clinical trials of HDL-raising drugs could be put to rest by using a better indicator of HDL status.
A multidisciplinary team at the University of Pittsburgh will be leading a national effort to explore the relationship between the bacteria that live in the lungs, gene activation patterns, and disease progression. The project, funded by a three-year, $8.3 million grant from the National Institutes of Health, intends to learn more about the causes and progression of two potentially deadly yet under-studied lung diseases, alpha-1 antitrypsin (A1AT) deficiency and sarcoidosis.
Pitt Public Health researchers have discovered that people who receive the most popular weight-loss surgical procedure are at an increased risk of developing symptoms of alcohol use disorders.
Violence ranks among the leading public health problems of young people and are more prevalent in areas of concentrated poverty. Efforts to de-concentrate poverty aim to improve the social conditions of low-income neighborhoods.