The Epidemiology Data Center (EDC) was established in 1980 as a section of the Department of Epidemiology in the Graduate School of Public Health at the University of Pittsburgh. It was founded by Katherine M. Detre, M.D., Dr.P.H., and is under the co-direction of Sheryl F. Kelsey, Ph.D., Steven H. Belle, Ph.D. and Stephen R. Wisniewski, Ph.D.

The EDC has collaborated in over 100 research studies sponsored by the National Institutes of Health and other agencies. Presently, the EDC coordinates data management and analysis activities for 26 research projects sponsored by federal agencies as well as by industry.

The current studies represent a variety of scientific designs including clinical trials, registries, and case control studies. The successful coordination of our research requires that we facilitate national and global communication among a number of institutions worldwide.

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Menopause: The Journal of the North American Menopause Society, January 2013
Substantial changes in the diameter and thickness of a section of carotid artery in perimenopausal women may indicate a higher risk of developing cardiovascular disease, the leading cause of death in women, according to a new study by researchers at the University of Pittsburgh Graduate School of Public Health.

JAMA, June 2012
As the prevalence of severe obesity increases in the United States, it is becoming increasingly common for health care providers and their patients to consider bariatric surgery, which is the most effective and durable treatment for severe obesity. Although bariatric surgery may reduce long-term mortality, and it carries a low risk of short-term serious adverse outcomes,safety concerns remain. Anecdotal reports suggest that bariatric surgery may increase the risk for alcohol use disorders (AUD; ie, alcohol abuse and dependence). However, only 3 studies have examined AUD before and after bariatric surgery.


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New research from the University of Pittsburgh suggests that doubts raised recently about the protective effects of high density lipoprotein (HDL), or “good,” cholesterol by a genetic study and several recent clinical trials of HDL-raising drugs could be put to rest by using a better indicator of HDL status.
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A multidisciplinary team at the University of Pittsburgh will be leading a national effort to explore the relationship between the bacteria that live in the lungs, gene activation patterns, and disease progression. The project, funded by a three-year, $8.3 million grant from the National Institutes of Health, intends to learn more about the causes and progression of two potentially deadly yet under-studied lung diseases, alpha-1 antitrypsin (A1AT) deficiency and sarcoidosis.
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Pitt Public Health researchers have discovered that people who receive the most popular weight-loss surgical procedure are at an increased risk of developing symptoms of alcohol use disorders.
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The Hepatitis B Research Network brings together clinical centers with expertise in caring for patients with chronic hepatitis B virus (HBV) infection. An estimated 2 billion people worldwide have been infected with HBV and about 400 million persons are living with chronic HBV infection.
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Violence ranks among the leading public health problems of young people and are more prevalent in areas of concentrated poverty. Efforts to de-concentrate poverty aim to improve the social conditions of low-income neighborhoods.