EDC Active Studies

The EDC is engaged in the research of 26 projects that include Aging, Cardiovascular, Mental Health, Women’s Health, Infectious Disease, Diabetes Studies, and others.


ADAPT – Approaches and Decisions in Acute Pediatric TBI Trial

Each year, TBIs contribute to a substantial number of deaths and cases of permanent disability. In fact, TBI is a contributing factor to a third (30.5%) of all injury-related deaths in the United States. On average, approximately 1.7 million people sustain a traumatic brain injury annually. read more »


CIRCA – Consortium for Injury Research and Community Action

The Consortium for Injury Research and Community Action (CIRCA) is a university-wide comprehensive Injury Control Research program that provides community based injury prevention, research, training, and service through an extensive collaboration with a broad range of university, state and local organizations. read more »


COAST – Clarifying the Optimal Application of SLT Therapy

Selective laser trabeculoplasty (SLT) has been a treatment option for newly diagnosed open-angle glaucoma or ocular hypertension for nearly 20 years. However, few studies have specifically compared multiple energy levels directly in a head-to-head fashion. The overall goal of the COAST Trial is to identify the optimal application of SLT therapy beginning at the time of diagnosis.  read more »


HBRN – Hepatitis B Research Network

The Hepatitis B Research Network brings together clinical centers with expertise in caring for patients with chronic hepatitis B virus (HBV) infection. An estimated 2 billion people worldwide have been infected with HBV and about 400 million persons are living with chronic HBV infection. read more »


INHIBIT – Hemophilia Inhibitor Prevention Trial

INHIBIT is a multicenter, randomized Clinical Trials Platform that includes two-linked randomized, multicenter phase III trials to Prevent and Eradicate Inhibitors in Severe Hemophilia A. read more »


LITES – Linking Investigations in Trauma and Emergency Services

The Linking Investigations in Trauma and Emergency Services (LITES) is a research network of US trauma systems and centers with the capability to conduct prospective, multicenter, injury care and outcomes research of relevance to the Department of Defense (DOD). read more »


MINT – Myocardial Ischemia and Transfusion

MINT is a multicenter randomized clinical trial comparing red blood cell transfusion strategies for patients who have had a myocardial infarction and are anemic. The trial will enroll 3500 hospitalized patients diagnosed with myocardial infarction who are anemic (have blood counts less than 10 g/dL) to receive either a liberal or a restrictive transfusion strategy. read more »


PTC – Pulmonary Trials Cooperative

The Pulmonary Trials Cooperative brings together research protocol leaders, clinical centers, and research participants to develop new treatments and test existing clinical management strategies. read more »


SCD-CARRE – Sickle Cell Disease and CardiovAscular Risk – Red cell Exchange Trial

The purpose of this study is to carefully evaluate the effects of giving long-term red blood cell exchange transfusion to a group of patients with SCD with certain risk factors for severe organ damage or early death. We want to know if regular exchange blood transfusion will minimize complications in patients with SCD or reduce the chances of new serious problems occurring in patients with sickle cell disease. read more »


SWAN – Study of Women’s Health Across the Nation

The Study of Women’s Health Across the Nation (SWAN) is a multi-site longitudinal, epidemiologic study designed to examine the health of women during their middle years. The study examines the physical, biological, psychological and social changes during this transitional period. read more »


TACTIC – Trans-Agency Consortium for Trauma-Induced Coagulopathy

TACTIC is the Trans-Agency Consortium for Trauma-Induced Coagulopathy. It is funded by the National Heart, Lung, and Blood Institute (NHLBI) and is a cooperative effort among the National Institutes of Health (NIH), the Department of Defense (DoD), the University of Vermont, and other research centers. The TACTIC team was assembled to study coagulation in trauma patients. read more »


Vit-D-Kids – Vitamin D Kids Asthma

This study will determine whether vitamin D3 helps to prevent severe asthma attacks in asthmatic children who are being treated with inhaled corticosteroids. Results from prior studies suggest that vitamin D reduces the risk of severe asthma attacks and that this protective effect may be due to immune modulation of viral illnesses or increased response to inhaled corticosteroids. read more »

Interested in Working with the EDC?

Collaboration with other institutions has always been essential to our work. Please contact us for more information on how working with the EDC can benefit your organization.


M-F, 8:30am to 5pm ET

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Mailing Address

Epidemiology Data Center
University of Pittsburgh
4420 Bayard Street, Suite 600
Pittsburgh, PA 15260


Collaboration with other institutions has always been essential to our work. Please contact us for more information on how working with the EDC can benefit your organization. research@edc.pitt.edu