Results of the 7-Year Follow-up of the LABS Project, which is coordinated by the EDC, are published online in JAMA Surgery

Dec 20, 2017 | News

In this multicenter longitudinal study, the 7-year weight and comorbid health changes following Roux-en-Y gastric bypass and laparoscopic adjustable gastric banding were assessed.

Seven years following Roux-en-Y gastric bypass participants had, on average, lost 28% of their initial weight, after having regained, on average, 4% of their initial weight between 3 and 7 years. These figures were 15% and 1%, respectively, following laparoscopic adjustable gastric banding. The prevalence of dyslipidemia was reduced 7 years following both procedures. Diabetes and hypertension prevalence were reduced following Roux-en-Y gastric bypass only; remission of diabetes at 7 years was 60.2% for Roux-en-Y gastric bypass. The authors conclude that most participants who underwent Roux-en-Y gastric bypass or laparoscopic adjustable gastric banding maintained the majority of their initial weight loss with variable fluctuations over the longer term, and that comorbid health improvements were sustained after Roux-en-Y gastric bypass.

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Anita P. Courcoulas, Wendy C. King, Steven H. Belle, Paul Berk, David R. Flum, Luis Garcia, William Gourash, Mary Horlick, James E. Mitchell, Alfons Pomp, Walter J. Pories, Jonathan Q. Purnell, Ashima Singh, Konstantinos Spaniolas, Richard Thirlby, Bruce M. Wolfe, Susan Z. Yanovski. Seven-Year Weight Trajectories and Health Outcomes in the Longitudinal Assessment of Bariatric Surgery (LABS) Study. JAMA Surg. Published online December 06, 2017. doi:10.1001/jamasurg.2017.5025